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DnaJ homolog, subfamily B, member 5 pseudogene (DNAJB5 pseudogene)
- Target
- DNAJB5 pseudogene
- Molecular classification
- Other (pseudogene), DNAJ/HSP40 protein family (ancestral/parental gene classification)
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Overview
DnaJ homolog, subfamily B, member 5 pseudogene (DNAJB5 pseudogene; ENSG00000276828) is an annotated human pseudogene. Pseudogenes are DNA segments similar in sequence to known genes but rendered inactive (nonfunctional) by mutation, deletion, or premature stop codons, thus unable to produce functional protein[3][8]. DNAJB5 pseudogene shares homology with the functional gene DNAJB5, which is a molecular chaperone in the Hsp40/DNAJ family, assisting in proper protein folding, refolding, and preventing aggregation[3][4]. Unlike its parental gene, no biological activity, functional domain, disease association, or druggability is ascribed to this pseudogene. In structured biomedical resources, pseudogenes are excluded from therapeutic target databases due to their lack of functional product.\n\nIf you need information about the functional DNAJB5, refer to \"DnaJ (Hsp40) homolog, subfamily B, member 5,\" omitting the pseudogene label[4].
- Other names
- DNAJB5PDnaJ (Hsp40) homolog, subfamily B, member 5 pseudogene
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