DNAJC9 antisense RNA 1 (DNAJC9-AS1)

DNAJC9 antisense RNA 1 (DNAJC9-AS1) is a long non-coding RNA (lncRNA) gene located on human chromosome 10 and annotated in major genomic databases (NCBI Gene ID: 414245, Ensembl: ENSG00000236756)[1][5][9]. It is transcribed as an antisense RNA relative to its neighboring DNAJC9 and MRPS16 genes. The known aliases for this gene include C10orf103 and bA537A6.3[1][5][6][9]. DNAJC9-AS1 is classified as a lncRNA, not as a protein-coding gene[2][9]. It is reported to be involved in **basic cellular processes** including cell proliferation, apoptosis, and migration[2]. The mechanistic details of its function are largely unexplored; however, like other lncRNAs, DNAJC9-AS1 is predicted to participate in **chromatin regulation** and **transcription factor modulation**[1]. These roles are based on dataset associations, histone modification site profiles, and transcription factor binding evidence at the gene’s promoter[1]. Clinical and experimental evidence for DNAJC9-AS1’s role in **disease** is limited. Some databases note a weak association with **glioma susceptibility**[9], and by analogy with other lncRNAs, there may be relevance in broader cancer contexts, but robust data are lacking[2]. There are **no known drugs** that directly interact with DNAJC9-AS1, nor established mechanisms of drug action, known biomarkers, or documented safety concerns[1][2][9]. This molecule is **not considered a conventional therapeutic target** (such as a receptor, enzyme, or transporter)[1][2][9]. Most research concerning DNAJC9-AS1 remains descriptive, focusing on expression profiles across tissues and cells, rather than on pharmacological or clinical targeting. In summary, **DNAJC9 antisense RNA 1 (DNAJC9-AS1)** is a long non-coding RNA with unclear and incompletely characterized molecular function, mainly implicated in general cellular regulatory processes and not considered a therapeutic target at present[1][2][9].

Other names

C10orf103bA537A6.3DNAJC9 and MRPS16 antisense RNA 1DNAJC9 antisense gene protein 1