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DNPEP antisense RNA 1 (DNPEP-AS1)

Target
DNPEP-AS1
Molecular classification
Other (Long non-coding RNA; lncRNA)
01

Overview

DNPEP antisense RNA 1 (DNPEP-AS1) is a human long non-coding RNA gene located on chromosome 2 (region 2q35, chr2:219,388,496-219,403,633, hg38 build), transcribed as an antisense RNA relative to the DNPEP (Aspartyl aminopeptidase) gene. This locus produces an RNA molecule but does not encode a protein. Its specific biological function, regulatory roles, or involvement in disease processes are currently not characterized or supported by available functional studies.\n\nKey clarifications:\n- DNPEP-AS1 should not be confused with the DNPEP gene, which encodes the aspartyl aminopeptidase enzyme, a metalloenzyme involved in protein metabolism. DNPEP (the enzyme) is a valid protein target; DNPEP-AS1, the lncRNA, is not.\n- Some databases (GeneCards, Ensembl, BioGPS) confirm the status of DNPEP-AS1 as a non-coding RNA and not a protein or “canonical” drug target.\n- There is no evidence that DNPEP-AS1 is studied as a biomarker, disease gene, or a relevant node in therapeutic development.\n\nSummary:\nDNPEP-AS1 is an uncharacterized long non-coding antisense RNA gene without evidence of being a protein, therapeutic target, or disease biomarker. There are no drugs, disease associations, or functional data supporting it as a therapeutic node. This entry appears in gene naming databases but lacks other characterization, and should not be listed as a typical “receptor,” “enzyme,” or “target.”

Other names
DNPEP-AS1DNPEP antisense RNA 1
02

Mechanism of action

None. No drugs target this RNA, so there are no mechanisms of drug action described for DNPEP-AS1

03

Biological functions

Currently uncharacterized. LncRNAs are generally involved in the regulation of gene expression at various levels (chromatin modification, transcriptional, post-transcriptional), but specific biological functions for DNPEP-AS1 are not described in publicly available data.
04

Disease associations

Unknown/Other. No documented association with diseases as of current knowledge
05

Safety considerations

None known.
06

Interacting drugs

None known. No drugs target DNPEP-AS1
07

Biomarkers

None documented.

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