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"Donor immune cell" is not a specific molecule, receptor, or canonical therapeutic target. Instead, this term refers broadly to any immune cell population transferred from a donor to a recipient, most commonly in the context of organ or hematopoietic stem cell transplantation[3][8][5]. Donor immune cells include a wide range of cell types such as T cells, B cells, dendritic cells, natural killer (NK) cells, and others present in the donated organ or graft. These cells play central roles in immunological phenomena after transplantation, such as graft-versus-host disease (GVHD), graft rejection, immune tolerance, and immune reconstitution[5][3][8][4]. As such, "donor immune cell" is not a structurally or functionally defined molecule or receptor, but a collective term describing the origin of diverse immune cell populations in transplantation settings. Therefore, it does not align with the conventions for structured therapeutic target information.
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