Target intelligence / Profile preview

Doublecortin domain-containing protein 2C (DCDC2C)

Target
DCDC2C
Molecular classification
Other (predicted cytoskeletal-associated protein, DCX domain protein)
01

Overview

Doublecortin domain-containing protein 2C (DCDC2C) is a member of the doublecortin (DCX) domain protein family, which are generally implicated in microtubule binding and stabilization, especially in the cytoskeleton and neuronal development[3][7][4]. For DCDC2C specifically, available evidence is limited to predictive annotations, with possible roles in intracellular signal transduction and localization to the cytoplasm and sperm flagellum[4][7]. There is no direct evidence of DCDC2C being a therapeutic target, nor documented small molecule or biologic ligands. The gene is listed in several databases with basic information, but lacks experimental validation of function, tissue specificity, or disease roles. Notes on correctness: - DCDC2C is listed as a *predicted* gene with limited functional evidence and is sometimes referred to as a "pseudogene" in certain sources, indicating there may be doubt as to whether it encodes a functional protein product in humans[7]. - It is not established in drug discovery or clinical literature as a therapeutic target. - There is a related and well-characterized gene DCDC2 (Doublecortin domain-containing protein 2), which is different from DCDC2C[1][5][6]. Care should be taken not to confuse the two.

Other names
Doublecortin domain containing 2CDCDC2Cdoublecortin domain containing 2C pseudogene
02

Biological functions

Predicted to be involved in intracellular signal transductioninferred association with microtubule dynamics, based on doublecortin domain functions in related proteins
03

Disease associations

No confirmed disease association for DCDC2Cgene family members (e.g., DCDC2) are noted in reading disorders (developmental dyslexia), but this is not established for DCDC2C

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