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Target intelligence / Profile preview
Doublesex- and mab-3-related transcription factor C1 (DMRTC1)
- Target
- DMRTC1
- Molecular classification
- Transcription factor
01
Overview
Doublesex- and mab-3-related transcription factor C1 (DMRTC1) is a member of the DMRT (doublesex and mab-3 related transcription factor) family and is associated with the regulation of DNA-templated transcription[5][6][8]. Unlike other members, DMRTC1 does not possess the canonical DM DNA-binding domain characteristic of the family[8]. The gene is located on chromosome X and encodes a protein believed to act in the nucleus, most likely in chromatin, in the regulation of transcription[5][7][8]. There are currently no known therapeutic drugs, biomarker applications or well-defined disease associations reported for DMRTC1.
- Other names
- DMRT like family C1doublesex-mab-3-related C1DMRT-like C1DMRTC1
02
Mechanism of action
None known (no drugs identified as targeting this factor)
03
Biological functions
Regulation of transcription (DNA-templated)Chromatin associationLikely role in transcription regulation
04
Disease associations
None clearly established; no direct roles in major diseases such as cancer, inflammation, or neurodegeneration have been documented in available sources
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