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Downy mildew pathogen (examples: Peronospora species, Plasmopara species, Bremia species)

Molecular classification
Oomycete (class), Peronosporales (order), Peronosporaceae (family), Obligate plant pathogen, Not fungi; Chromista kingdom
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Overview

Downy mildew pathogens are a diverse group of oomycete microorganisms (not true fungi) that are obligate parasites of living plant tissue. They infect a broad range of crops and ornamentals, causing some of the world's most destructive plant diseases and leading to significant agricultural losses worldwide. Downy mildew species are highly host-specific, and a single species will often only infect a narrow range of related plants. Typical symptoms include angular yellow spots on leaf surfaces, downy patches of sporangia on leaf undersides, and rapid destruction of foliage under wet, cool conditions. Common genera responsible for downy mildew include Peronospora, Plasmopara, Bremia, Pseudoperonospora, and Sclerospora. Traditional management relies on resistant plant varieties and cultural practices, with limited chemical options due to resistance and safety concerns. Molecular diagnostic tools are increasingly important for species identification and monitoring.

Other names
Downy mildewDowny mildew oomycetesDowny mildew pathogensOomycete pathogens (downy mildew)
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Mechanism of action

Inhibition of sporangia/zoospore development in oomycetes (protectant/curative fungicides); Disruption of cell wall synthesis or mitochondrial function in oomycetes

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Biological functions

Plant parasitismInduction of plant diseaseHost-specific virulenceSporulation and dissemination via airborne spores
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Disease associations

Infection (particularly plant infection)Agricultural loss (crop damage)Plant disease
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Safety considerations

Fungicide residue on cropsFungicide resistance (emerging problem due to widespread fungicide use)Environmental toxicity of some chemical protectantsDifficulty of eradicating pathogens due to obligate parasitism and host specificity
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Interacting drugs

Oxadixyl

4 more in the full profile.

07

Biomarkers

Pathogen-specific DNA/RNA sequences (for molecular diagnostics)Foliar symptomology: angular yellow lesions with sporulation on the leaf undersideOospore and sporangia detection (microscopy)

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