Target intelligence / Profile preview

DPH5 divergent transcript (DPH5-DT)

Target
DPH5-DT
Molecular classification
Other (non-coding RNA, divergent transcript)
01

Overview

"DPH5 divergent transcript" (DPH5-DT) is a transcript produced from the genomic region near the DPH5 gene, transcribed in the opposite (divergent) orientation. Divergent transcripts like this are commonly produced at gene promoters and typically result in short, unstable non-coding RNAs, also known as promoter upstream transcripts (uaRNAs) or divergent non-coding RNAs. The specific function, if any, of this transcript is unknown, and it is not recognized as a protein-coding gene, therapeutic target, or disease marker. The canonical DPH5 is a methyltransferase required for diphthamide biosynthesis on eEF2, but the divergent transcript has no such function and remains biologically uncharacterized.

Other names
DPH5 divergent transcriptDPH5-DT
02

Mechanism of action

None known.

03

Biological functions

No specific or characterized biological function is known for this transcript
04

Disease associations

No established role in disease for this transcript

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