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Dpy-30 homolog pseudogene (ENSG00000256843) is a pseudogene corresponding to the functional DPY30 gene. Unlike its functional gene counterpart—which encodes the DPY-30 subunit of the COMPASS complex that regulates histone H3K4 methylation and influences cell differentiation[2][4]—this pseudogene does not encode a functional protein. Pseudogenes, including this one, are generally the result of gene duplication or retrotransposition events followed by disabling mutations. There is no evidence supporting a protein product or active biological function for this specific pseudogene in humans[1][3]. It should not be mistaken for the protein-coding DPY30 gene, which has clear roles in chromatin regulation[2][4]. Note: - The entry "dpy-30 homolog pseudogene" should not be considered a viable drug or research target. - If structured, DPY30 (the active protein-coding gene) and dpy-30 homolog pseudogene (this entity) must be kept distinct, as only the former encodes a functional protein of biomedical interest[4].
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