Target intelligence / Profile preview

DPY19L2 pseudogene 1 (DPY19L2P1)

Target
DPY19L2P1
Molecular classification
Other (pseudogene; derived from transmembrane protein family)
01

Overview

DPY19L2 pseudogene 1 (DPY19L2P1) is a non-coding pseudogene located in a genomic region syntenic to the functional mouse Dpy19l2 gene[1][2][4]. It originates from a gene duplication and relocation event, and subsequent inactivation (pseudogenization) resulted in loss of protein-coding potential[1][4]. DPY19L2P1 shares high sequence identity with the functional DPY19L2 gene, a member of a novel transmembrane gene family involved in sperm development and related to globozoospermia when mutated, but DPY19L2P1 itself does not encode a functional protein nor does it play a known biological or pathological role[1][2][4]. It is expressed at low levels in some tissues, though this expression does not result in a functional product[1].

Other names
Putative C-mannosyltransferase DPY19L2P1Dpy-19-like protein 2 pseudogene 1Protein dpy-19 homolog 2-like 1
02

Biological functions

Other (DPY19L2P1 does not have known biological functions; it is a non-functional pseudogene. Functional roles are associated with its parent gene, DPY19L2, not with DPY19L2P1 itself)
03

Disease associations

Other (No established disease roles for DPY19L2P1. Mutations in the related functional gene, DPY19L2, cause globozoospermia, but DPY19L2P1 itself is not implicated)

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