DPY19L2 pseudogene 4 (DPY19L2P4)

**DPY19L2 pseudogene 4 (DPY19L2P4)** is a human pseudogene derived from the duplication and subsequent inactivation of the DPY19L2 gene. Pseudogenes like DPY19L2P4 are sequences in the genome that closely resemble functional genes but are rendered non-functional by disabling mutations, such as frameshifts or premature stop codons. DPY19L2P4 shares high sequence identity with the active DPY19L2 gene, which encodes a transmembrane protein involved in spermatogenesis, but due to disabling mutations (e.g., in-frame stop codons), DPY19L2P4 does not code for a functional protein[1][3]. Like other members of the DPY19L family, it is part of a transmembrane gene family primarily expressed in the testis; however, the pseudogene itself has no known biological function, disease role, or therapeutic relevance. DPY19L2P4 is not considered a drug target, biomarker, or associated with any disease or safety concerns[1][3]. **Note:** - The functional counterpart, DPY19L2, is implicated in male infertility, but pseudogenes such as DPY19L2P4 do not have such roles[5][4]. - DPY19L2P4 is best classified as a "pseudogene" rather than a receptor, enzyme, transporter, or other therapeutically relevant biological target[1][3].

Other names

DPY19L2P4IMAGE:5295327