Dual specificity phosphatase 3 pseudogene (null)

Dual specificity phosphatase 3 pseudogene (LOC100420466, ENSG00000214254) is a genomic sequence highly similar to the functional DUSP3 gene, but lacks known expression of an active enzyme or protein product. Pseudogenes like LOC100420466 arise from duplication or retrotransposition events and typically serve no direct cellular function, though rare exceptions may occur in other contexts. LOC100420466 is not implicated in disease, does not interact with drugs, and is not considered a therapeutic, diagnostic, or research target[1]. Important note: - This pseudogene is not the same as DUSP3 (Dual specificity phosphatase 3), which encodes a functional MAPK phosphatase associated with cell cycle regulation and immune signaling[4][6][7]. - The functional DUSP3 protein is a member of the enzyme family of phosphatases and is sometimes investigated as a therapeutic target in cancer and immune regulation, but this pseudogene (LOC100420466) possesses neither enzymatic activity nor therapeutic relevance[1].

Other names

LOC100420466Dual specificity phosphatase 3 pseudogeneENSG00000214254

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