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Dual specificity phosphatase 8 pseudogene 1 (DUSP8P1) is classified as a pseudogene in humans, meaning it closely resembles the gene for dual specificity phosphatase 8 (DUSP8) but does not encode a functional protein. Unlike the canonical DUSP8 gene, which codes for a protein involved in dephosphorylating MAP kinase targets and regulating cellular signaling, DUSP8P1 lacks protein-coding function and is not considered an enzyme, receptor, or therapeutic target. There is no validated biological function, disease association, drug interaction, or biomarker relevance for DUSP8P1 itself. Its presence has been mapped to chromosome 10q11.2. The nomenclature sometimes overlaps with the protein-coding DUSP8, which is a distinct and bona fide therapeutic target. It is crucial to distinguish DUSP8P1 as a pseudogene from the functional DUSP8.
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