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Target intelligence / Profile preview
Dynactin subunit 5 (DCTN5)
- Target
- DCTN5
- Molecular classification
- Other (Protein complex subunit)
01
Overview
DCTN5 encodes a subunit of the dynactin complex, which is crucial for dynein-dependent microtubule transport. Dynactin is involved in various cellular processes, including intracellular trafficking and regulation of disease-related mechanisms in neurodegeneration and cancer. While DCTN5 is not typically considered a therapeutic target like receptors or enzymes, it plays a significant role in cellular processes and disease pathophysiology. Its involvement in intracellular transport and potential as a prognostic biomarker in certain cancers make it an important biological molecule for research.
- Other names
- Dynactin subunit p25MGC3248p25
02
Mechanism of action
Not applicable
03
Biological functions
Intracellular transportMicrotubule transportLysosomal traffickingCellular processes regulation
04
Disease associations
CancerNeurodegenerative diseaseKidney disease
05
Biomarkers
Lower levels of DCTN5 associated with favorable survival in cutaneous melanoma
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