Dynamin 1 pseudogene 46 (DNM1P46)

Dynamin 1 pseudogene 46 (DNM1P46) is a processed pseudogene related to the dynamin 1 gene (DNM1), which encodes a mechanochemical GTPase essential for clathrin-mediated endocytosis and synaptic vesicle recycling[1][3][5]. However, DNM1P46 itself does not encode a functional protein; as a pseudogene, it is not involved in protein synthesis or recognized biological pathways, nor is it a therapeutic target, disease gene, or biomarker. The canonical full-length gene, DNM1, plays important roles in neuronal function and is linked to epilepsy and other neurodevelopmental disorders[1][5]; these disease associations do not apply to DNM1P46. There are no known drugs, mechanisms of action, or safety concerns associated with DNM1P46. Additional context: - Pseudogenes are genetic elements that resemble protein-coding genes but are typically non-functional due to mutations or lack of regulatory elements. - The association of the "Putative GED domain-containing protein" in aliases reflects sequence homology only; DNM1P46 does not produce a functional GED domain-containing protein. - If you are seeking information about the functional dynamin 1 gene or protein, that is a GTPase involved in vesicle scission during endocytosis, but this does not apply to DNM1P46[1][3][5].

Other names

Putative GED domain-containing protein DNM1P46C15orf51DNM1DN14.2FLJ45937DKFZp434I1020DNM1 pseudogene 46