Dynamin 1 pseudogene 48 (DNM1P48)

Dynamin 1 pseudogene 48 (DNM1P48) is classified as a pseudogene, meaning it is a genomic DNA sequence similar to a functional gene (dynamin 1, DNM1) but is generally non-functional, typically not transcribed or translated into a protein[1]. The canonical functional gene, dynamin 1, encodes a large GTPase critical for clathrin-mediated endocytosis and vesicular trafficking in neurons, and is involved in several neurological and cancer processes[1][2]. However, there are over sixty conserved copies of DNM1-like pseudogene sequences elsewhere in the human genome, especially on chromosomes Y and 15, and these copies (such as DNM1P48) are not known to encode functional proteins or have recognized roles in physiology or pathology[1]. Thus, DNM1P48 itself is not a receptor, enzyme, transporter, or drug target, nor is it implicated in disease or therapeutics. If you are seeking information on the functional protein dynamin 1 or its therapeutic relevance, refer instead to the actual DNM1 gene and its associated protein, dynamin 1[1][2].

Other names

DNM1P48