Target intelligence / Profile preview

Ectodomain Vimentin

Molecular classification: Intermediate Filament Protein, Receptor, Co-receptor

Overview

Ectodomain vimentin refers to the cell-surface-exposed or extracellular form of vimentin, an intermediate filament protein. While traditionally known for its intracellular role in providing structural support, ectodomain vimentin acts as a receptor or co-receptor for pathogens and modulates immune responses. It is implicated in cancer progression, metastasis, and inflammatory diseases, making it a potential therapeutic target and biomarker.

Biological functions

Cell adhesionCell migrationPathogen bindingImmune modulationStructural support

Disease associations

Cancer progressionMetastasisViral infectionInflammation

Biomarkers

Cancer progressionMetastasisInflammation

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