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Target intelligence / Profile preview
EEF1A1 antisense RNA 1 (EEF1A1-AS1)
- Target
- EEF1A1-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Natural antisense transcript (NAT)
01
Overview
EEF1A1 antisense RNA 1 (EEF1A1-AS1) is a naturally occurring long non-coding RNA transcribed from the DNA strand antisense to the EEF1A1 protein-coding gene. NATs such as EEF1A1-AS1 can regulate the expression of their corresponding sense gene (often modulating mRNA stability, splicing, or translation), and may play broader regulatory roles in cell biology. While some NATs have been implicated in disease processes such as cancer, there is no direct evidence provided here on disease involvement for EEF1A1-AS1 specifically.
- Other names
- EEF1A1-AS1 lncRNALong non-coding RNA EEF1A1 antisense RNA 1
02
Mechanism of action
For NATs in general, mechanisms include binding to complementary sense mRNA to modulate its stability, splicing, or translation.
03
Biological functions
Regulation of gene expressionModulation of chromatin structureRNA stability and processing
04
Disease associations
CancerOther diseases via regulation of their sense gene expression
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