Target intelligence / Profile preview

EF-hand calcium-binding domain-containing protein 14 (EFCAB14)

Target
EFCAB14
Molecular classification
Calcium-binding protein, EF-hand domain-containing protein
01

Overview

EF-hand calcium-binding domain-containing protein 14 (EFCAB14) is a human protein characterized by the presence of EF-hand motifs, which are helix–loop–helix structures that bind calcium ions with high specificity[1][2][3]. EFCAB14 is involved in calcium signaling pathways inside cells and likely plays a regulatory role in various cellular processes dependent on calcium flux, such as those related to neuronal and cardiovascular function[1][3]. While antibodies and detection kits for EFCAB14 exist for research use, there are currently no drugs or therapeutic mechanisms known to target this specific molecule, and it is not currently classified as a therapeutic target such as a receptor, enzyme, transporter, or transcription factor[1][3]. Its gene annotations include calcium ion binding activity and predicted membrane localization[3]. There is no evidence of EFCAB14 being established as a biomarker or as having safety concerns related to clinical targeting.

Other names
KIAA0494EF-hand calcium-binding domain 14EF-hand calcium-binding domain-containing protein 14EFCAB14
02

Biological functions

Calcium signalingRegulation of cellular processes
03

Disease associations

Neurodegenerative diseaseCardiovascular diseaseOther

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