EFCAB6 antisense RNA 1 (EFCAB6-AS1)

EFCAB6 antisense RNA 1 (EFCAB6-AS1), also known as CITF22-123F2.1, is a long non-coding RNA (lncRNA) classified as an antisense transcript. Antisense RNAs, including EFCAB6-AS1, are RNA molecules transcribed from the DNA strand opposite to the sense (protein-coding) gene—which in this case is likely the EFCAB6 gene. These molecules typically regulate gene expression in cis (affecting the neighboring gene locus) or in trans (acting on other loci), often through mechanisms involving chromatin modification, mRNA stability, or transcriptional interference[1]. While the detailed biological roles and disease associations of EFCAB6-AS1 have not been independently characterized in the literature, the general class of antisense RNAs has been implicated in diverse biological processes, especially in the epigenetic regulation of gene expression and in the development or progression of cancer[1]. No approved drugs, mechanisms of action, biomarkers, or safety concerns have been specifically reported for EFCAB6-AS1. Note: Information about EFCAB6-AS1 specifically is extremely limited in public scientific repositories. Most available knowledge pertains to the general class of antisense RNAs and well-studied examples like HOTAIR. Additional details about EFCAB6, the protein-coding sense gene, do not apply directly to its antisense RNA and are not included here[2][3].

Other names

CITF22-123F2.1