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EGFLAM antisense RNA 4 (EGFLAM-AS4)
- Target
- EGFLAM-AS4
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA
01
Overview
EGFLAM antisense RNA 4 (EGFLAM-AS4) is a non-protein coding antisense long non-coding RNA located on chromosome 5. It is transcribed from the opposite strand of the EGFLAM gene, which encodes EGF-like, fibronectin type III and laminin G domains protein. EGFLAM-AS4 is annotated in genomic databases (NCBI Gene: 100852408, Ensembl: ENSG00000248730), but its molecular function and disease relevance remain largely uncharacterized. Like other antisense lncRNAs, it may influence the expression and regulation of its sense gene (EGFLAM), but specific regulatory activity or pathological roles have not been described.
- Other names
- CTD-2022B6.1EGFLAM antisense RNA 4 (non-protein coding)EGFLAM-AS4
02
Biological functions
Possible regulation of EGFLAM gene expression via antisense mechanismsGeneral roles attributed to antisense lncRNAs include transcriptional modulation, post-transcriptional regulation, and epigenetic regulation in diverse biological contexts
03
Disease associations
No direct disease associations reported for EGFLAM-AS4 itself as of nowIn general, antisense lncRNAs can influence cellular proliferation, migration, and have been implicated in cancer biology. However, there is currently no disease linkage assigned specifically to EGFLAM-AS4.
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