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Eicosanoid Synthesis Pathway

Molecular classification: Metabolic Pathway

Overview

The eicosanoid synthesis pathway refers to the series of enzymatic reactions that convert polyunsaturated fatty acids (PUFAs), primarily arachidonic acid (AA), into a diverse group of bioactive lipid mediators known as eicosanoids. These molecules play critical roles in inflammation, immunity, vascular tone regulation, and other physiological processes.

Mechanism of action

Modulation of cyclooxygenases

Biological functions

Modulation of inflammatory responsesRegulation of vascular tone and blood pressureMediation of immune cell functionInfluencing platelet aggregation and hemostasis

Disease associations

Inflammatory disordersCardiovascular diseasesAsthma/allergies

Interacting drugs

NSAIDs

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