Eicosanoid synthetic pathway

The **eicosanoid synthetic pathway** refers to the collection of enzymatic reactions that convert membrane phospholipids—primarily arachidonic acid—into bioactive eicosanoids, including prostaglandins, thromboxanes, leukotrienes, lipoxins, and related molecules. The key enzyme families involved are cyclooxygenases (COX), lipoxygenases (LOX), and cytochrome P450 monooxygenases (CYP), which generate diverse lipid mediators that regulate inflammation, vascular tone, hemostasis, and immunity. This pathway is central to the pathogenesis and resolution of many diseases, but as a term, it is not a single therapeutic target; rather, it encompasses multiple distinct enzymatic and molecular targets[1][3][4][6].

Other names

Eicosanoid biosynthesisEicosanoid pathwayEicosanoid metabolism