Target intelligence / Profile preview

Elongin A3 family member D, pseudogene (ELOA3DP)

Target
ELOA3DP
Molecular classification
Pseudogene, Other
01

Overview

**Elongin A3 family member D, pseudogene (ELOA3DP)** is classified as a pseudogene and not a protein-coding gene[1][7]. It is annotated as a likely pseudogene of Elongin A (ELOA) and is not known to encode a functional protein. While the SIII (elongin) transcription elongation factor complex—composed of functional Elongin A family members—stimulates RNA polymerase II transcription elongation, ELOA3DP itself does not code for a functional member of this complex. There is no evidence it is biologically active as a therapeutic target, and it is not associated with drugs, mechanisms of action, biomarkers, or roles in disease beyond sequence similarity with related loci[1][7]. ELOA3DP is a nonfunctional genomic element rather than an active receptor, enzyme, transporter, or transcription factor. Its primary scientific relevance comes from its relationship to other, functional Elongin A3 retrogenes found in primates that may participate in RNA polymerase II regulation, but ELOA3DP itself is not biologically active[1][3][7].

Other names
ELOA3DELOA3L2TCEB3CL2RNA polymerase II transcription factor SIII subunit A3-like-2eloA3-like-2elongin A3 like 2elongin-A3 member Dtranscription elongation factor B polypeptide 3C-like-2transcription elongation factor B subunit 3C like 2ELOA3DPTCEB3CELOA3

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