Elongin B pseudogene 2 (ELOBP2)

Elongin B pseudogene 2 (ELOBP2, also known as TCEB2P2) is a human pseudogene related to the Elongin B gene (TCEB2). Pseudogenes are DNA sequences similar to functional genes but are typically non-functional due to mutations or deletions, and they are usually not transcribed into functional proteins. ELOBP2 does not code for a protein product and is not involved in canonical biological pathways, disease processes, or targeted pharmacology[4][5][6]. Key context: - ELOBP2 is a pseudogene and not a protein-coding gene or a functional receptor, enzyme, or other druggable target[5][6]. - It shares sequence similarity with the functional Elongin B gene, which is involved in transcription elongation and ubiquitination pathways; however, ELOBP2 does not have a known biological function[4][5][6]. - Because it is a pseudogene, there are no known drugs, disease associations, mechanisms of drug action, biomarker roles, or safety concerns[5][6]. - Listings in standard gene databases and gene compendia confirm this pseudogene status, distinguishing it from the functional Elongin B (ELOB), which is a regulatory protein in key complexes[5][6][4]. Thus, **ELOBP2 is not a functional therapeutic target**, and its primary relevance is in genomics rather than molecular or clinical pharmacology[5][6].

Other names

TCEB2P2Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) pseudogene 2Elongin B pseudogene 2Transcription elongation factor B subunit 2 pseudogene 2Transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) pseudogene