Elongin C pseudogene 12 (ELOCP12)

Elongin C pseudogene 12 (ELOCP12) is classified as a **pseudogene** in the human genome, meaning it is a non-functional remnant of a gene related to the protein-coding gene elongin C (ELOC)[2]. ELOC encodes elongin C, a regulatory subunit of transcription elongation factor B (SIII), which is involved in transcriptional regulation and ubiquitination processes central to oxygen sensing and protein degradation[1][3]. However, **ELOCP12 itself does not produce a functional protein** and is not implicated in biological pathways or disease either as a direct effector or a therapeutic target[2]. **Interpretation and context:** - The canonical protein-coding gene (ELOC) is functionally important, but ELOCP12 refers to a pseudogene copy, not to an active gene product, enzyme, or receptor. - There is no evidence that ELOCP12 is involved in any disease process, targeted by drugs, or serves as a biomarker or biological effector. - The confusion often arises between the pseudogene and the canonical gene; the former (ELOCP12) is not a valid target, while the latter (ELOC) is involved in biologically significant pathways[1][2][3]. **Summary of critical points:** - **ELOCP12 is a pseudogene, not a protein, enzyme, or receptor.** - **It is not considered a therapeutic target.** - **It does not possess known molecular, biological, or disease-related functions.** - **No drugs, biomarkers, or safety issues are associated with it.**

Other names

TCEB1P12transcription elongation factor B (SIII), polypeptide 1 pseudogene 12transcription elongation factor B subunit 1 pseudogene 12ELOCP12