Target intelligence / Profile preview

Enamel Hydroxyapatite Crystals (HA)

Target
HA
Molecular classification
Mineral, Inorganic Material, Biomaterial
01

Overview

Enamel hydroxyapatite crystals are the primary inorganic component of dental enamel, comprising 92–97% of its weight. They are responsible for the hardness and durability of tooth enamel. While not a direct drug target, its integrity is crucial for dental health and is influenced by various substances like fluoride.

Other names
HydroxyapatiteCalcium Phosphate HydroxideTooth Enamel Crystals
02

Mechanism of action

Fluoride promotes the formation of fluorapatite, a more acid-resistant mineral. Remineralizing agents deposit calcium and phosphate ions to repair enamel.

03

Biological functions

Structural component of teethProtection against physical wearProtection against chemical attack
04

Disease associations

Dental cariesTooth erosionTooth sensitivity
05

Interacting drugs

Fluoride

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