Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Tooth enamel is the most mineralized and hardest tissue in the human body, covering the anatomic crown of teeth as a thin, hard, and highly mineralized layer. Composed of approximately 95–98% inorganic calcium phosphate (as carbonated hydroxyapatite), about 1% organic matrix (mainly enamel-specific proteins: amelogenin, enamelin, ameloblastin), and the remainder water, enamel provides structural integrity, mechanical protection, and resistance to wear and acid attack during chewing and exposure to foods. Enamel does not contain cells, blood vessels, or nerves, and cannot regenerate after formation. Its crystalline rods are susceptible to demineralization by acid and are thus the focus of preventive dental treatments.
Fluoride: promotes remineralization and inhibits demineralization of enamel hydroxyapatite; Calcium phosphate: provides ions for remineralization; Sealants: form physical barrier over enamel
2 more in the full profile.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Explore the programs pursuing this target and their development progress.
Follow the clinical studies evaluating therapies directed at this target.
Compare approaches across drug candidates, modalities, and indications.
Investigate the research and source evidence behind target biology and development.
Explore patent activity around therapies and technologies addressing this target.
Connect target biology, drug development, and emerging evidence in your research.
See how Gosset can support your research on Enamel surface of tooth.