Endo-exonuclease (N/A)

Endo-exonucleases are enzymes that possess both endonuclease and exonuclease activities, allowing them to cleave nucleic acids internally and from the ends. These enzymes play crucial roles in DNA repair, genetic recombination, and mutation avoidance. Examples include the MRX complex and the SbcCD complex. They are considered therapeutic targets due to their involvement in DNA processing and repair pathways. Inhibition or modulation of their activity could have implications for cancer treatment, antiviral strategies, or management of genetic disorders.

Other names

Dual nucleaseEnzymes with both endonuclease and exonuclease activityProteins with both endonuclease and exonuclease activityProteins or complexes with endo- and exonuclease activities

Inhibition of DNA repair, promotion of DNA degradation