Endogenous Bornavirus-like nucleoprotein 3, pseudogene (EBLN3P)

Endogenous Bornavirus-like nucleoprotein 3, pseudogene (EBLN3P) is a pseudogene-derived long non-coding RNA found in the human genome[1][5]. Unlike protein-coding genes, pseudogenes like EBLN3P do not produce functional proteins but can regulate gene expression through RNA-mediated mechanisms[2]. Recent research indicates that EBLN3P is upregulated in osteosarcoma, where it acts as a competitive endogenous RNA (ceRNA), sponging microRNA miR-224-5p and modulating Rab10 expression, ultimately promoting tumor cell proliferation, migration, and invasion[2]. Although EBLN3P has no direct links as a therapeutic target or drug interactor, its regulatory role in cancer biology makes it a research interest for future diagnostic or prognostic approaches[2][5]. This molecule is best classified as a pseudogene-derived long non-coding RNA involved in cancer-related gene regulation, not as a classical drug target or receptor[2][5].

Other names

LOC100506710EBLN3endogenous Bornavirus-like nucleoprotein 2 pseudogeneEBLN3P

Not applicable; drugs do not target EBLN3P. Mechanistically, EBLN3P acts as a sponge for microRNAs (e.g., miR-224-5p) affecting gene expression networks related to cancer progression