Target intelligence / Profile preview

Endometrial Cell Integrins (N/A)

Target: N/A
Molecular classification: Cell Adhesion Molecules, Transmembrane Receptors

Overview

Endometrial cell integrins are a family of cell adhesion molecules that mediate cell-cell and cell-ECM interactions within the endometrium. They play crucial roles in tissue integrity, cellular signaling, and dynamic remodeling processes such as those occurring during the menstrual cycle and implantation. Aberrant expression patterns are associated with various infertility conditions.

Other names: Uterine IntegrinsEndometrial Adhesion Molecules

Mechanism of action

N/A

Biological functions

Cell-Cell AdhesionCell-Extracellular Matrix AdhesionSignal TransductionEmbryo ImplantationDecidualizationTissue RemodelingUterine Receptivity

Disease associations

InfertilityEndometriosis-associated InfertilityLuteal Phase DeficiencyRecurrent Pregnancy LossUnexplained InfertilityHydrosalpinx

Biomarkers

αvβ3 expression (uterine receptivity)β3 subunit expression (window of implantation)

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