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Target intelligence / Profile preview
Endometrium
- Molecular classification
- Tissue
01
Overview
The endometrium is the innermost lining of the uterus, composed of the stratum basalis (regenerative layer) and the stratum functionalis (shedding layer). It plays a central role in menstruation, implantation, and placental development under hormonal control by estrogen and progesterone. Abnormalities in endometrial thickness and function can indicate or cause infertility, endometriosis, hyperplasia, or cancer.
- Other names
- tunica mucosa uteriuterine mucosa
02
Mechanism of action
Hormonal regulation of proliferation and shedding
03
Biological functions
Menstrual cyclingImplantation supportPlacenta formationPrevention of adhesions between opposing walls of myometrium
04
Disease associations
InfertilityEndometriosisEndometrial hyperplasiaUterine/endometrial cancer
05
Safety considerations
Abnormal thickening indicating hyperplasia or cancerPotential complications from hormone therapy
06
Interacting drugs
Estrogen
2 more in the full profile.
07
Biomarkers
Endometrial thickness
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