Endoplasmic reticulum lumenal protein 29 pseudogene 1 (ERP29P1)

Endoplasmic reticulum lumenal protein 29 pseudogene 1 (ERP29P1), also known as ERP28P, is a processed pseudogene found in the human genome[3]. Unlike functional protein-coding genes, pseudogenes like ERP29P1 have lost their coding potential due to disabling mutations or lack of regulatory sequences, and thus do not encode functional proteins[2][3]. Pseudogenes may sometimes play regulatory roles, such as acting as microRNA decoys or producing non-coding RNAs that influence the expression of related genes, but no evidence is available that ERP29P1 itself serves such a regulatory function[2][3]. The functional gene related to ERP29P1 is ERp29, an endoplasmic reticulum protein involved in protein folding and secretion, and which has been implicated in cancer biology and ER stress responses[1]. However, ERP29P1 itself is considered a non-functional pseudogene, not a valid drug target, biomarker, or receptor[3][2]. Key Notes on Accuracy: ERP29P1 is a pseudogene, not an active protein, enzyme, receptor, transporter, or traditional therapeutic target[3][2]. It should not be confused with the functional ERp29 protein, which is sometimes discussed as a target in cancer and protein homeostasis research[1]. No clinical, therapeutic, or biomarker data supports any role for ERP29P1 itself. If this molecule was referenced as a direct drug or diagnostic target, this is *incorrect*.

Other names

ERP28P