Target intelligence / Profile preview

Endoplasmic reticulum membrane (ER membrane)

Target
ER membrane
Molecular classification
Other
01

Overview

Other names
ER membraneSarcoplasmic reticulum membraneMicrosomal membraneMitochondria-associated ER membraneMAM
02

Mechanism of action

Induction of terminal endoplasmic reticulum stress, inhibition of calcium transport via the sarco/endoplasmic reticulum Ca}

03

Biological functions

Protein foldingLipid synthesisCalcium homeostasisSignal transductionApoptosis
04

Disease associations

CancerNeurodegenerative diseaseInflammationMetabolic disorder
05

Interacting drugs

Bortezomib

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