Endosomal transmembrane epsin interactor 3 (ENTREP3)

Endosomal transmembrane epsin interactor 3 is a protein encoded by the ENTREP3 gene[4][5]. It is described as a potential binding partner of a WW domain-containing protein involved in apoptosis and tumor suppression[4]. Its sequence and domain structure suggest possible analogy to the epsin family of endocytic adaptor proteins involved in protein trafficking, signaling, and potentially cell migration and invasion—although direct function and clinical relevance for ENTREP3 itself remain poorly characterized. Disease associations include some neoplasms and cancer phenotypes, but evidence is largely indirect or inferred from related proteins. Alternative splicing leads to multiple transcript variants[4]. No direct drug interactions or targeted therapeutics have been reported for this protein. \nIf you require more structured details or want to confirm specific disease or functional aspects (e.g., direct evidence for endocytosis or adaptor roles), more functional genomics or proteomics data may be necessary. Current public sources provide limited molecular characterization, largely associating the protein with potential protein-protein interactions and as a member of a family with disease relevance[4][3][6].

Other names

FAM189BC1orf2GC01M155261GC01M155307GC01M155371GC01M155420GC01M155488GC01M156440GC01M157760GC01M158824GC01M159913GC01M161107GC01M163975GC01M165115GC01M166340