Endothelin converting enzyme like 1 pseudogene 1 (ECEL1P1)

Endothelin converting enzyme like 1 pseudogene 1 (ECEL1P1) is a pseudogene, not a protein-coding or functional gene, and therefore does not encode a functional protein or act as a therapeutic or molecular target[2]. Unlike its parent gene, ECEL1, which encodes a zinc-dependent metalloprotease involved in neuropeptide processing, ECEL1P1 is classified as non-coding and is not associated with any known biological function, disease role, or drug interaction. Pseudogenes like ECEL1P1 generally result from gene duplication or retrotransposition events and accumulate mutations that prevent them from producing functional proteins; as such, they are not considered valid therapeutic targets nor associated with mechanism of action or safety concerns[2]. Notes: - Endothelin converting enzyme like 1 pseudogene 1 (ECEL1P1) should not be confused with the functional Endothelin converting enzyme like 1 (ECEL1), which encodes an active enzyme involved in neuropeptide regulation and disease (see ECEL1, not ECEL1P1)[2][3][7]. - ECEL1P1 is not considered a molecular target or involved in disease mechanisms at the current state of knowledge. - Most genomic databases and literature list it solely as a processed pseudogene with no additional aliases or known functional roles[2].