Endovascular stent graft

"Mechanical fixation of endovascular grafts" refers to the engineering and deployment strategies used to secure endovascular stent grafts within the aorta during procedures like endovascular aneurysm repair (EVAR), primarily for treating abdominal or thoracic aortic aneurysms.[1][3][4] These grafts are fabric tubes reinforced by metal stents (e.g., nitinol) that are inserted via femoral artery access under fluoroscopy, expanding to reline the aneurysm sac and exclude it from blood pressure, thereby preventing rupture.[1][2][4][5][6] Fixation mechanisms include passive radial force from self-expanding stents and active elements like barbs, hooks, or EndoAnchors to anchor against vessel walls, ensuring stability in proximal and distal seal zones.[3][4][8] This approach offers a minimally invasive alternative to open surgery, with shorter procedure times (1-4 hours), reduced morbidity, and high freedom from aneurysm rupture (98% at 9 years in some cohorts), though long-term surveillance is required for complications.[2][3][5] Challenges include anatomical suitability (e.g., adequate neck length), endoleaks, and reinterventions in 35-38% of cases over 8 years.[3][4] No specific molecular target or drug interactions apply, as this is a mechanical intervention rather than pharmacological modulation.[1][3][4]

Other names

Endovascular aneurysm repair (EVAR)stent graftendovascular graftESG