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Enterovirus 3C Protease (None)
- Target
- None
- Molecular classification
- Enzyme, Cysteine protease
01
Overview
Enterovirus 3C protease (3C^pro) is a cysteine protease encoded by enteroviruses that is essential for viral replication and pathogenesis. It functions by processing the viral polyprotein, modulating host cell functions, and antagonizing host innate immune responses. Due to its critical role, it is an attractive target for antiviral drug development.
- Other names
- 3C protease3CproEV-A71 3C proteaseEV-D68 3C protease
02
Mechanism of action
Inhibition of viral polyprotein processing and immune evasion by blocking 3C protease activity.
03
Biological functions
Polyprotein processingViral replicationInhibition of innate immunityApoptosis induction
04
Disease associations
InfectionHand-foot-and-mouth diseaseSevere respiratory illness
05
Safety considerations
Off-target effects on host proteasesDevelopment of drug resistance
06
Interacting drugs
Luteoloside
1 more in the full profile.
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