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Entry Inhibitor
- Molecular classification
- Antiviral drug class
01
Overview
Entry inhibitors are a class of antiviral drugs that prevent viruses, most notably HIV, from entering host cells. They achieve this by interfering with the binding, fusion, or entry processes required for viral infection. By blocking these early steps in the viral life cycle, entry inhibitors help slow disease progression and are especially valuable in combination antiretroviral therapy. They target various stages of the virus-cell entry process, including pre-attachment, post-attachment, co-receptor binding, and membrane fusion.
02
Mechanism of action
Blocks virus attachment/fusion/entry into host cell
03
Biological functions
Inhibition of viral entryAntiviral activity
04
Disease associations
HIV infectionViral infections
05
Safety considerations
Resistance developmentTropism switchingSide effects specific to individual drugs within the class
06
Interacting drugs
Fostemsavir
4 more in the full profile.
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