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"Environmental modification" refers to the intentional or unintentional alteration of the natural environment by organisms (including humans) or environmental factors, often resulting in changes to ecosystems, resource availability, and biological interactions[3][2]. Examples include human-driven changes such as agriculture, dam construction, afforestation, or urban development, as well as microbial activities that alter environmental parameters like pH or oxygen[2][3]. This term is sometimes used in ecology, environmental science, and occasionally in discussions of microbial community dynamics or environmental epigenetics, but it is never used as the name of a drug target, receptor, protein, or defined molecular entity in biomedical research[3][5][2].
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