Target intelligence / Profile preview

Eosinophil (EOS)

Target: EOS
Molecular classification: Leukocyte, Granulocyte, Immune cell

Overview

Eosinophils are a type of white blood cell (leukocyte) classified as granulocytes due to their prominent cytoplasmic granules. They play a crucial role in the immune system, particularly in defending against multicellular parasites and participating in allergic reactions and asthma. Eosinophils are not directly druggable, but rather their activity or recruitment is modulated by targeting cytokines, receptors, or other immune mediators.

Mechanism of action

N/A

Biological functions

Defense against parasitic infectionsModulation of allergic responsesParticipation in hypersensitivity reactionsImmune response

Disease associations

Allergic diseasesParasitic infectionsAsthmaInflammation

Safety considerations

Eosinophil-mediated tissue damageUncontrolled degranulation

Biomarkers

Eosinophil count (CBC)

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