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Eosinophil Granulocyte
- Molecular classification
- Leukocyte, Granulocyte, Immune cell
01
Overview
Eosinophil granulocytes are a type of white blood cell belonging to the granulocyte family. They are characterized by their bi-lobed nucleus and large cytoplasmic granules that stain red with acidic dyes. Eosinophils play a role in host defense against parasites, modulation of allergic responses, and participation in inflammatory reactions. Elevated levels of eosinophils are associated with various diseases, including parasitic infections, allergic diseases, and autoimmune disorders. Excessive activation and degranulation of eosinophils can contribute to tissue injury in chronic inflammatory and allergic conditions.
- Other names
- EosinophilEosinophil granulocyteEosinophilic leukocyte
02
Biological functions
Host defense against parasitic helminthsModulation of allergic responsesParticipation in inflammatory reactionsImmunomodulatory functionsTissue remodeling during chronic inflammationRelease of toxic granule proteinsCytokine secretionLipid mediator release
03
Disease associations
Parasitic infectionsAllergic diseases/asthmaAutoimmune disordersMalignanciesChronic inflammatory conditions
04
Safety considerations
Tissue damage due to degranulationExacerbation of allergic reactionsContribution to chronic inflammation
05
Biomarkers
Eosinophil count in bloodEosinophil count in tissues
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