Target intelligence / Profile preview

EP300 interacting inhibitor of differentiation 2 pseudogene (EID2 pseudogene)

Target
EID2 pseudogene
Molecular classification
Pseudogene, Other
01

Overview

EP300 interacting inhibitor of differentiation 2 pseudogene (ENSG00000227842) is classified as a human pseudogene, meaning it is a genomic locus with high sequence similarity to a known gene (in this case, the EP300 interacting inhibitor of differentiation 2, or EID2), but it is unable to encode a functional protein product due to loss-of-function mutations or absence of necessary regulatory sequences[1][3]. Pseudogenes like this one are remnants of evolutionary processes and may very rarely have functions such as serving as microRNA decoys, generating noncoding RNAs, or regulating the transcription of their "parent" or related genes, but there is *no evidence of such function for this specific locus*[6][8]. It is not a therapeutic target, receptor, transporter, or enzyme, and it is not implicated in disease pathogenesis or drug activity[1][3][8]. In summary: ENSG00000227842 is a pseudogene, not a therapeutic target, and should not be used as a canonical drug or target entity for structured pharmacological or biomedical databases[1][3].

Other names
EID2 pseudogeneGC02P112475GC02P111819GC02P111833
02

Mechanism of action

None. There are no pharmacological effects mediated by this locus[1][3].

03

Biological functions

No primary protein-coding functionPotential, but rare, regulatory roles in gene expression via RNA decoys or antisense mechanisms, described in a few cases for other pseudogenesMost pseudogenes, including this one, are considered nonfunctional remnants of protein-coding genes
04

Disease associations

None known for this specific pseudogeneSome pseudogenes (not this one specifically) have been implicated in disease through regulatory effects, but there is no evidence for a role in cancer, inflammation, or other disease for this locus

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