Target intelligence / Profile preview

Epididymal protein 3B (EDDM3B)

Target: EDDM3B
Molecular classification: Secreted protein, Epididymal protein family

Overview

Epididymal protein 3B (EDDM3B) is a secreted protein encoded by the EDDM3B gene, primarily expressed by epithelial cells lining the human epididymal duct. It is implicated in the process of sperm maturation and is believed to play a role in modifying the sperm membrane as spermatozoa transit through the epididymis. There is currently no evidence for its role as a therapeutic target, nor for involvement in recognized human diseases or drug interactions[1][2][3][8].

Other names: EP3BFAM12BHE3BHE3-BETAHuman epididymis-specific protein 3-betaEpididymal secretory protein E3-betaRAM2Ribonuclease A M2

Biological functions

Sperm maturationPossibly involved in modification of sperm membrane during epididymal transit

Disease associations

No reported major disease associations

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