Epididymal-specific lipocalin-10 (LCN10)

**Lipocalin-10** (LCN10), also known as epididymal-specific lipocalin-10, is a member of the lipocalin protein family characterized by a conserved β-barrel structure that binds small hydrophobic molecules. LCN10 is produced in the human epididymis and is thought to play a role in the transport of small molecules during sperm maturation, although its precise biological or disease-related functions are not well defined. Lipocalins, in general, participate in the carriage and sequestration of diverse ligands and in some cases modulate immune responses[1][2][3][5]. **Clarifications and limitations:** - “Lipocalin 10” (canonical: LCN10) is a genuine human protein but is **not recognized as a therapeutic target** (e.g., not a receptor, enzyme, transporter, or validated drug target). - There are no established drug interactions, mechanisms of action, biomarkers, or known disease associations for LCN10. - The lipocalin family encompasses a variety of small extracellular proteins with diverse functions, but not all, including LCN10, are clinically targeted or directly implicated in major diseases[1][2][3][5]. **Summary:** Lipocalin-10 (LCN10) is a human extracellular protein of the lipocalin family, primarily expressed in the epididymis, with presumed transport and possibly immunomodulatory roles, but is **not considered a therapeutic target** nor associated with known drug interactions or specific disease roles under current scientific understanding[1][2][3][5].

Other names

LCN10Lipocalin-10Epididymal secretory protein E1