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Epigenetic Modulator

Molecular classification: Enzyme, Histone modification, Transcription factor, Other

Overview

An epigenetic modulator is a molecule—often a protein or small compound—that regulates gene expression by altering the structure or chemical modifications of chromatin, without changing the underlying DNA sequence. These modulators play crucial roles in controlling which genes are turned on or off in a cell, thereby influencing cellular identity, function, and response to environmental cues.

Mechanism of action

Regulates gene expression by altering chromatin structure or chemical modifications (DNA methylation, histone modification, chromatin remodeling, non-coding RNAs)

Biological functions

Regulation of gene expressionCell differentiationTissue developmentEnvironmental adaptationOther

Disease associations

CancerNeurodegenerative diseaseMetabolic disordersOther

Interacting drugs

DNMT inhibitors (e.g., larsucosterol)

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