ER degradation enhancer, mannosidase alpha-like 1 pseudogene (ENSG00000228480)

ER degradation enhancer, mannosidase alpha-like 1 pseudogene (ENSG00000228480) is annotated as a *pseudogene* related to the functional gene *EDEM1* (ER degradation-enhancing alpha-mannosidase-like protein 1)[3]. Pseudogenes are genomic sequences similar to known genes but do not encode functional proteins due to mutations such as frameshifts or premature stop codons[7]. Recent research indicates some pseudogenes can play regulatory roles at the RNA level, such as acting as microRNA decoys or generating small RNAs, potentially modulating the expression of their parent or related genes[5][7]. However, there is no direct evidence that this specific pseudogene is involved in protein coding, therapeutic targeting, or well-characterized disease pathways. In summary, ENSG00000228480 is not a protein-coding gene or validated therapeutic target, but a pseudogene, and should not be considered a canonical receptor, enzyme, or other druggable molecular entity at this time[3][5][7].

Other names

EDEM1 pseudogeneER degradation enhancer mannosidase alpha-like 1 pseudogene[3]