Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Erythroid differentiation regulator 1 (ERDR1)
- Target
- ERDR1
- Molecular classification
- Secreted protein, Cytokine-like factor
01
Overview
Erythroid differentiation regulator 1 (ERDR1) is a secreted, highly conserved protein involved in regulating cell growth homeostasis, apoptosis, immune responses, and tissue repair. It acts as a multifunctional molecule influencing cell proliferation and death balance, with concentration-dependent effects. ERDR1 also plays a crucial role in immune modulation by influencing T-cell function and macrophage polarization. Furthermore, it promotes wound healing through the induction of CCL2 production and activation of MAP kinase pathways. Therapeutic potential exists in cancer, skin diseases, and rheumatoid arthritis.
02
Mechanism of action
Induces or suppresses cellular proliferation/survival depending on concentration/cell density. Triggers apoptotic pathways via caspase activation and modulation of key regulators like Bcl‑2/Bax. Engages multiple signaling cascades including MAPKs and Hippo-YAP axis.
03
Biological functions
Cell growth homeostasisApoptosis regulationImmune modulationWound healingTissue repairCell proliferationCell deathCytokine production
04
Disease associations
CancerSkin DiseasesRosaceaRheumatoid ArthritisInflammation
Beyond the preview
Go deeper on Erythroid differentiation regulator 1 (ERDR1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Erythroid differentiation regulator 1 (ERDR1).