Establishment of cohesion 1 homolog 1 pseudogene (ENSG00000254888)

Establishment of cohesion 1 homolog 1 pseudogene (ENSG00000254888) is a nonfunctional DNA sequence in the human genome, showing high sequence similarity (homology) to the functional ESCO1 gene but lacking the ability to encode a functional protein product. Pseudogenes such as this may arise from gene duplication or retrotransposition, followed by subsequent disabling mutations. While most pseudogenes are not functionally active, some can be transcribed into non-coding RNAs and occasionally have regulatory effects on other genes. However, there is no evidence that ENSG00000254888 acts as a therapeutic target, nor are drugs known to interact with it. Its presence may complicate genetic studies due to sequence similarity with ESCO1, but it is not considered a protein-coding or regulatory gene of clinical significance.

Other names

ESCO1 pseudogeneEstablishment of cohesion 1 homolog 1, pseudogeneESCO1P (noting that it is not a true gene)

None applicable