ETS2 pseudogene 1 (ETS2P1)

ETS2 pseudogene 1 (ETS2P1) is a noncoding DNA sequence located on the X chromosome that closely resembles the functional ETS2 gene but contains mutations that prevent it from producing a functional protein[1][3]. Pseudogenes, such as ETS2P1, arise from gene duplication or retrotransposition and typically do not serve as direct therapeutic targets because they are unable to encode proteins or perform biological actions[3]. Although most pseudogenes are regarded as nonfunctional, a small number can exert regulatory effects in certain contexts, but there is no known evidence that ETS2P1 plays such a role[3]. Key point: ETS2P1 is a pseudogene and not a therapeutically relevant target, nor does it encode a functional protein. All relevant therapeutic functions and disease associations pertain to the canonical ETS2 gene, not the pseudogene[1][3][4].

Other names

ETS2P1

None (no mechanisms of drug action apply to pseudogenes)